p-Methoxybenzoic Acid Introduction
Chemical Name: p-Methoxybenzoic Acid
Synonyms: p-Anisic Acid, 4-Anisic Acid
CAS Number: 100-09-4
Molecular Formula: C8H8O3
Molecular Weight: 152.15 g/mol
Physicochemical Properties
Appearance: Colorless needle-like crystals, stable at room temperature, non-volatile.
Solubility: Readily soluble in ethanol, ether, and chloroform; slightly soluble in hot water; sparingly soluble in cold water.
Melting Point: 198–201 °C. Chemically stable, forms salts with bases.
Precautions: Avoid prolonged contact with strong oxidizing agents. Handle and store in a dry place, protected from moisture and light.
Synthesis and Preparation Methods
p-Methoxybenzoic acid is commonly synthesized via the oxidation of p-methoxybenzaldehyde or carboxylation of p-methoxyphenol. These processes are well-established and suitable for large-scale industrial production. The product purity can be enhanced through recrystallization or column chromatography to meet the high standards of the pharmaceutical and fine chemical industries.
Main Application Fields
Pharmaceutical Intermediate: Widely used in the synthesis of anti-inflammatory drugs, antibacterial agents, and other organic pharmaceuticals.
Fragrance Industry: Serves as a precursor for fragrances and food flavorings, enhancing aroma stability.
Dyes and Pigments: Functions as an intermediate for dyes and raw material for functional organic materials.
Organic Chemical Reagent: Participates in various organic reactions such as esterification, coupling, and condensation.
Market Value and Advantages
High purity and strong stability, suitable for continuous industrial production.
Convenient and safe handling, meeting the demands of various industries including pharmaceuticals, chemicals, and fragrances.
Holds significant search relevance for terms like "p-methoxybenzoic acid uses" and "p-Anisic Acid synthesis methods".
Safety and Storage
Store in a tightly sealed container in a cool, dry place, protected from direct sunlight and moisture.
Wear appropriate protective equipment during handling to prevent inhalation of dust or skin contact.
Avoid storage in close proximity to strong oxidizing agents.