Structure and Application Analysis of Tetramethylethylenediamine (TMEDA)

English Name: N,N,N′,N′-Tetramethylethylenediamine (TMEDA)

CAS No.: 110-18-9

Chromatographic Purity: ≥99.0%

Molecular Weight: 116.2

Flash Point: 50 °F

Physical Form: Liquid

Refractive Index: n20/D 1.4179 (lit.)

Density: 0.775 g/mL at 20 °C (lit.)

Applications: Pharmaceutical intermediate

Main Functions:

N,N,N′,N′Tetramethylethylenediamine  is a colorless transparent liquid with a slight ammonia odor. It is miscible with water and most organic solvents such as ethanol. TMEDA is an important organic intermediate widely used as a biochemical reagent, epoxy resin crosslinking agent, and as an intermediate in the synthesis of quaternary ammonium compounds.

Production Process of Tetramethylethylenediamine

Tetramethylethylenediamine (CAS No. 110-18-9) is a widely used organic chemical. Due to its unique structure and chemical properties, it plays a significant role across various industries. This article explores its structural formula, chemical characteristics, and applications in different fields.

I. Structure and Properties of TMEDA

The molecular structure of TMEDA can be represented as CH₃–N–CH₂–CH₂–N–CH₃, consisting of two nitrogen atoms each bonded to two methyl groups (CH₃). It is a colorless liquid with a mild ammonia-like odor and is soluble in water, alcohols, and ethers.

Structure Analysis:

The molecular design of TMEDA makes it a highly effective amine compound. The presence of two nitrogen atoms and methyl groups imparts notable chemical reactivity. TMEDA is frequently used as a catalyst, reagent, and chelating agent in various chemical reactions.

II. Application Fields of TMEDA

N,N,N′,N′Tetramethylethylenediamine  is widely used in chemistry, pharmaceuticals, agriculture, and materials science. Major application areas include:

1. Chemical Catalysts and Reagents

In organic synthesis, TMEDA is commonly used as a catalyst and reagent, particularly in the synthesis of aldehydes, ketones, and amines. It enhances reaction efficiency and selectivity in several key reactions.

2. Polymerization Reactions

TMEDA serves as a chain initiator or crosslinking agent in polymerization processes, especially in the production of polyurethanes, polyesters, and epoxy resins.

3. Pharmaceutical Industry

TMEDA is used in the synthesis of pharmaceutical intermediates. Its special structure offers excellent activity in drug synthesis and functional group transformations.

4. Agrochemicals

As an organic amine compound, TMEDA is utilized in the synthesis of pesticides, herbicides, and plant growth regulators.

III. Market Prospects of TMEDA

Thanks to its wide range of applications, N,N,N′,N′Tetramethylethylenediamine  has strong global market demand. With the continuous development of the pharmaceutical, material, and chemical industries, the demand for TMEDA is expected to grow further. Especially in developing countries such as China and India, the market potential is considerable.

IV. How to Select a Reliable TMEDA Supplier

When selecting a TMEDA supplier, enterprises should consider the following aspects:

Product Quality: Choose suppliers with strict quality control systems to ensure the product meets international standards.

Supply Chain Stability: The supplier should have stable production capacity and delivery timelines to ensure consistent supply.

Technical Support and Services: Strong technical support and after-sales service help customers resolve technical issues during application.

Conclusion

N,N,N′,N′Tetramethylethylenediamine , as an essential chemical intermediate, has become indispensable across various industries due to its unique molecular structure and broad applicability. Whether in catalysis, polymerization, pharmaceutical synthesis, or agrochemical production, it plays a critical role. When choosing a TMEDA supplier, companies should focus on product quality, supply stability, and technical support to ensure a long-term, stable partnership.