p-Methoxybenzoic Acid Introduction​

p-Methoxybenzoic Acid Introduction

Chemical Name: p-Methoxybenzoic Acid

Synonyms: p-Anisic Acid, 4-Anisic Acid

CAS Number: 100-09-4

Molecular Formula: C8H8O3

Molecular Weight: 152.15 g/mol

Physicochemical Properties

Appearance: Colorless needle-like crystals, stable at room temperature, non-volatile.

Solubility: Readily soluble in ethanol, ether, and chloroform; slightly soluble in hot water; sparingly soluble in cold water.

Melting Point: 198–201 °C. Chemically stable, forms salts with bases.

Precautions: Avoid prolonged contact with strong oxidizing agents. Handle and store in a dry place, protected from moisture and light.

Synthesis and Preparation Methods

p-Methoxybenzoic acid is commonly synthesized via the oxidation of p-methoxybenzaldehyde or carboxylation of p-methoxyphenol. These processes are well-established and suitable for large-scale industrial production. The product purity can be enhanced through recrystallization or column chromatography to meet the high standards of the pharmaceutical and fine chemical industries.

Main Application Fields

Pharmaceutical Intermediate: Widely used in the synthesis of anti-inflammatory drugs, antibacterial agents, and other organic pharmaceuticals.

Fragrance Industry: Serves as a precursor for fragrances and food flavorings, enhancing aroma stability.

Dyes and Pigments: Functions as an intermediate for dyes and raw material for functional organic materials.

Organic Chemical Reagent: Participates in various organic reactions such as esterification, coupling, and condensation.

Market Value and Advantages

High purity and strong stability, suitable for continuous industrial production.

Convenient and safe handling, meeting the demands of various industries including pharmaceuticals, chemicals, and fragrances.

Holds significant search relevance for terms like "p-methoxybenzoic acid uses" and "p-Anisic Acid synthesis methods".

Safety and Storage

Store in a tightly sealed container in a cool, dry place, protected from direct sunlight and moisture.

Wear appropriate protective equipment during handling to prevent inhalation of dust or skin contact.

Avoid storage in close proximity to strong oxidizing agents.